| Fixture | Kick-Off | |
|---|---|---|
| Arsenal 1-0 Crystal Palace | 26/10/2025 14:00:00 | Preds |
| Aston Villa 1-0 Manchester City | 26/10/2025 14:00:00 | Preds |
| Bournemouth 2-0 Nottingham Forest | 26/10/2025 14:00:00 | Preds |
| Brentford 3-2 Liverpool | 25/10/2025 20:00:00 | Preds |
| Chelsea 1-2 Sunderland | 25/10/2025 15:00:00 | Preds |
| Everton 0-3 Tottenham Hotspur | 26/10/2025 16:30:00 | Preds |
| Leeds United 2-1 West Ham United | 24/10/2025 20:00:00 | Preds |
| Manchester United 4-2 Brighton & Hove Albion | 25/10/2025 17:30:00 | Preds |
| Newcastle United 2-1 Fulham | 25/10/2025 15:00:00 | Preds |
| Wolverhampton Wanderers 2-3 Burnley | 26/10/2025 14:00:00 | Preds |