| Fixture | Kick-Off | |
|---|---|---|
| Arsenal 3-1 Bayern Munich | 26/11/2025 20:00:00 | Preds |
| Atlético Madrid 2-1 Internazionale | 26/11/2025 20:00:00 | Preds |
| Liverpool 1-4 PSV Eindhoven | 26/11/2025 20:00:00 | Preds |
| Eintracht Frankfurt 0-3 Atalanta | 26/11/2025 20:00:00 | Preds |
| Olympiakos 3-4 Real Madrid | 26/11/2025 20:00:00 | Preds |
| Paris SG 5-3 Tottenham Hotspur | 26/11/2025 20:00:00 | Preds |
| Sporting CP 3-0 Club Brugge | 26/11/2025 20:00:00 | Preds |
| Pafos 2-2 Monaco | 26/11/2025 17:45:00 | Preds |
| FC Copenhagen 3-2 Kairat Almaty | 26/11/2025 17:45:00 | Preds |
| Slavia Prague 0-0 Athletic Bilbao | 25/11/2025 20:00:00 | Preds |
| Manchester City 0-2 Bayer 04 Leverkusen | 25/11/2025 20:00:00 | Preds |
| Marseille 2-1 Newcastle United | 25/11/2025 20:00:00 | Preds |
| Napoli 2-0 Qarabag | 25/11/2025 20:00:00 | Preds |
| Bodø/Glimt 2-3 Juventus | 25/11/2025 20:00:00 | Preds |
| Borussia Dortmund 4-0 Villarreal | 25/11/2025 20:00:00 | Preds |
| Chelsea 3-0 Barcelona | 25/11/2025 20:00:00 | Preds |
| Ajax 0-2 Benfica | 25/11/2025 17:45:00 | Preds |
| Galatasaray 0-1 Union Saint-Gilloise | 25/11/2025 17:45:00 | Preds |
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