| Fixture | Kick-Off | |
|---|---|---|
| Ajax 0-3 Galatasaray | 05/11/2025 20:00:00 | Preds |
| Atlético Madrid 3-1 Union Saint-Gilloise | 04/11/2025 20:00:00 | Preds |
| Benfica 0-1 Bayer 04 Leverkusen | 05/11/2025 20:00:00 | Preds |
| Bodø/Glimt 0-1 Monaco | 04/11/2025 20:00:00 | Preds |
| Club Brugge 3-3 Barcelona | 05/11/2025 20:00:00 | Preds |
| Internazionale 2-1 Kairat Almaty | 05/11/2025 20:00:00 | Preds |
| Juventus 1-1 Sporting CP | 04/11/2025 20:00:00 | Preds |
| Liverpool 1-0 Real Madrid | 04/11/2025 20:00:00 | Preds |
| Manchester City 4-1 Borussia Dortmund | 05/11/2025 20:00:00 | Preds |
| Marseille 0-1 Atalanta | 05/11/2025 20:00:00 | Preds |
| Napoli 0-0 Eintracht Frankfurt | 04/11/2025 17:45:00 | Preds |
| Newcastle United 2-0 Athletic Bilbao | 05/11/2025 20:00:00 | Preds |
| Olympiakos 1-1 PSV Eindhoven | 04/11/2025 20:00:00 | Preds |
| Pafos 1-0 Villarreal | 11/05/2025 17:45:00 | Preds |
| Paris SG 1-2 Bayern Munich | 04/11/2025 20:00:00 | Preds |
| Qarabag 2-2 Chelsea | 05/11/2025 17:45:00 | Preds |
| Slavia Prague 0-3 Arsenal | 04/11/2025 17:45:00 | Preds |
| Tottenham Hotspur 4-0 FC Copenhagen | 04/11/2025 20:00:00 | Preds |
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